Premios 40 Principales is an awards ceremony hosted annually by the Spanish radio channel Los 40 Principales. Gaga has been nominated three times.
| Year | Nominated work | Award | Result |
|---|---|---|---|
| 2009 | "Poker Face" | Los 40 Principales Award for Best International Song in a Foreign Language | Nominated |
| 2010 | "Bad Romance" | Los 40 Principales Award for Best International Song in a Foreign Language | Won |
| Lady Gaga | Los 40 Principales Award for Best International Artist in a Foreign Language | Won |